Tiderius CJ, Olsson LE, Leander P, Ekberg O, Dahlberg L. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in early knee osteoarthritis. Magn Reson Med 2003; 49:488 –492 [Google Scholar] 11.

Welcome to this guide regarding osteoarthritis (OA, or degenerative joint disease) of the knee. This Decision Guide is designed for persons who have learned… What can we help you find? Enter search terms and tap the Search button. Both arti

Magnetic resonance in medicine 49:488–492 cartilage improves the quality of T1 maps and provides a good 12. 2014-5-1 The “delay” refers to the time that is required for the contrast agent to diffuse into the cartilage after an intravenous (IV) injection. In femoral knee cartilage, T1 Gd was found to be relatively stable at 90–120 min postinjection, which has been the recommended window for dGEMRIC imaging of the knee [8, 11].In the hip joint, early data indicated no difference in signal intensity in T1 Methods: Between August 2008 and April 2012, sixty-five patients (seventy-four hips) underwent primary hip arthroscopy with preoperative dGEMRIC and a minimum of two years of follow-up. Exclusion criteria were previous hip surgery, slipped capital femoral epiphysis, inflammatory arthropathy, Legg-Calve-Perthes disease, and arthritis of >1 MRI with dGEMRIC provides quantitative information on cartilage quality, and lower dGEMRIC values were found for clock positions with impingement detected on 3D-CT. This could be helpful for a patient-specific diagnosis, to identify cartilage injuries, and to avoid … VAS, radiographs, dGEMRIC MRI, IgG isolation from plasma and synovial fluid: 17 (32 knees) Age: 40-85 Sex: M-F: 12-5 K-L: III-IV: 12 months: Significant decrease in VAS scores.

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2014-1-9 · MRI dGEMRIC summary Objective: To assess knee cartilage quality and subjective knee function, 20 years after injury in anterior cruciate ligament (ACL) injured copers. Method: We examined 32 knees using delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC), 20 years after a complete ACL tear. In knees at risk of developing OA, dGEMRIC values at baseline have been shown to be predictive of radiographic signs of knee OA 6 years later 29.The aim of the present study was to evaluate knee cartilage quality 20 years after ACL injury, in a group of individuals who had not been treated with ACL reconstruction (ACLR) and in whom there was no radiographic evidence of overt OA, using dGEMRIC. dGEMRIC (delayed gadolinium-enhanced MRI of cartilage) dGEMRIC, or delayed gadolinium-enhanced MRI of cartilage is a technique that can be used quantitatively to assess glycosaminoglycan content of cartilage or qualitatively to asses the overall structures of cartilage. When the technique is adapted and applied to menisci it is called dGEMRIM. Request PDF | Knee cartilage assessment with MRI (dGEMRIC) and subjective knee function in ACL injured copers: A cohort study with a 20 year follow-up | To assess knee cartilage quality and The majority of dGEMRIC studies have been in the knee and hip, although there are a number of reports of dGEMRIC applied to the finger joints [12, 50–52] and ankle .

Purpose. measures relative proteoglycan content of articular cartilage. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage or dGEMRIC measures the fixed-charge density and relative proteoglycan content of articular cartilage using the spin-lattice relaxation time or T1 relaxation time. Current research is investigating the clinical application of dGEMRIC as a quantitative tool for monitoring cartilage function in diseased or repair cartilage.

The method is robust, but requires injection of contrast agent and a cumbersome examination procedure. Read "dGEMRIC (delayed gadolinium‐enhanced MRI of cartilage) indicates adaptive capacity of human knee cartilage, Magnetic Resonance in Medicine" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Arthritis Rheum delayed gadolinium enhanced MRI of cartilage (dGEMRIC) of the 64:1697–1707 knee at 3.0T in patients with early stage osteoarthritis. Eur Radiol 23: 6.

Single- vs. double-dose gadolinium contrast in delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in knee osteoarthritis: is dose reduction possible on  

dGEMRIC (delayed gadolinium-enhanced MRI of cartilage) indicates adaptive capacity of human knee cartilage. Tiderius, Carl Johan LU ; Svensson, Jonas LU ; Leander, Peter LU ; Thorsson, Ola LU and Dahlberg, Leif LU ( 2004 ) In Magnetic Resonance in Medicine 51 (2) .

MRI dGEMRIC summary Objective: To assess knee cartilage quality and subjective knee function, 20 years after injury in anterior cruciate ligament (ACL) injured copers. Method: We examined 32 knees using delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC), 20 years after a complete ACL tear. dGEMRIC (delayed gadolinium‐enhanced MRI of cartilage) indicates adaptive capacity of human knee cartilage Carl Johan Tiderius Department of Orthopedics, Malmö University Hospital, Lund University, Malmö, Sweden Abstract. Delayed contrast‐enhanced MRI of cartilage (dGEMRIC) is a noninvasive technique to study cartilage glycosaminoglycan (GAG) content in vivo. This study evaluates dGEMRIC in patients with preradiographic degenerative cartilage changes. Seventeen knees in 15 patients (age 35–70) with arthroscopically verified cartilage changes (softening and fibrillations) in the medial or lateral femoral compartment, knee pain, and normal weight‐bearing radiography were included.
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2014-5-1 The “delay” refers to the time that is required for the contrast agent to diffuse into the cartilage after an intravenous (IV) injection. In femoral knee cartilage, T1 Gd was found to be relatively stable at 90–120 min postinjection, which has been the recommended window for dGEMRIC imaging of the knee [8, 11].In the hip joint, early data indicated no difference in signal intensity in T1 Methods: Between August 2008 and April 2012, sixty-five patients (seventy-four hips) underwent primary hip arthroscopy with preoperative dGEMRIC and a minimum of two years of follow-up. Exclusion criteria were previous hip surgery, slipped capital femoral epiphysis, inflammatory arthropathy, Legg-Calve-Perthes disease, and arthritis of >1 MRI with dGEMRIC provides quantitative information on cartilage quality, and lower dGEMRIC values were found for clock positions with impingement detected on 3D-CT. This could be helpful for a patient-specific diagnosis, to identify cartilage injuries, and to avoid … VAS, radiographs, dGEMRIC MRI, IgG isolation from plasma and synovial fluid: 17 (32 knees) Age: 40-85 Sex: M-F: 12-5 K-L: III-IV: 12 months: Significant decrease in VAS scores.

N Engl J Med. 2008 Sep. 11;359(11):1108-15. 2.
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Delayed gadolinium-enhanced MRI of menisci and cartilage (dGEMRIM/dGEMRIC) in obese patients with knee osteoarthritis : Cross-sectional study of 85 obese patients with intra-articular administered gadolinium contrast.

22 In OA, the highly negatively charged GAG are lost and when intravenously injected, the MRI contrast agent gadolinium Purpose. measures relative proteoglycan content of articular cartilage. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage or dGEMRIC measures the fixed-charge density and relative proteoglycan content of articular cartilage using the spin-lattice relaxation time or T1 relaxation time. Current research is investigating the clinical application of dGEMRIC as a quantitative tool for monitoring cartilage function in diseased or repair cartilage.